Do Statins Cause Erectile Dysfunction? – REX MD

High cholesterol is a risk factor for many conditions, including erectile dysfunction (ED). This is typically due to how high cholesterol levels can affect blood flow around the body. statins erectile dysfunction There are a number of prescription and over-the-counter drugs that may cause erectile dysfunction. While these drugs may treat a disease or condition, they can also affect a man’s hormones, nerves Statins are commonly prescribed for cardiovascular diseases which have been reported to share many contributory underlying mechanisms with erectile dysfunction (ED). However, the correlation between statin use and incident ED is uncertain.

Potency process and efficacy process charts are introduced to clarify and illustrate the relationships between six key concepts: MOA, potency, potency test, efficacy, efficacy Learn the difference between drug efficacy and potency, and how they affect the biological response of a drug. Drug efficacy is the maximum effect a drug can produce, while drug potency is the amount of potency vs efficacy Efficacy is estimated by comparing differences in the highest response at high drug concentrations or doses. On the other hand, Potency is estimated by comparing dose (ED50). The goal of efficacy research is to establish cause-and-effect relationships between independent (e.g, intervention) and dependent variables (e.g, symptoms). To conclude that one variable (e.g, behavioral intervention for sleep) has actually caused a change in another variable (e.g, number of hours sleeping each night) requires special attention to experimental control or internal validity Further, efficacy trials are designed to answer the question of whether a drug, device or intervention works at all while effectiveness studies help answer whether that intervention can help patients. In this sense, efficacy relies more on results statistical significance whereas effectiveness relates more to results clinical significance.